Michael or Mike Clifford may refer to:
Michael Clifford (journalist), Irish author and journalist
Michael Clifford (musician) (born 1995), Australian guitarist, bandmember of 5 Seconds of Summer
Michael R. Clifford (1952–2021), American army officer and astronaut
Michael B. Clifford, British filmmaker
Michael K. Clifford, American education investor and advisor
Mike Clifford (born 1943), American singer
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